Rheumatoid Arthritis Glossary
Real RA patients share their experiences on CIMZIA.
Analgesics:
Medications that relieve pain. Commonly used over-the-counter analgesics include aspirin, acetaminophen, ibuprofen, and naproxen. Others are available only by prescription.1
Anti-TNF:
A class of biologic drugs that suppress the immune system by de-activating a protein called tumor necrosis factor-alpha (TNF alpha) that has a role in causing inflammation in the joints. Cimzia is an example of an Anti-TNF. 1,2
Biologic response modifiers:
These drugs target and block proteins in the immune system that play a role in triggering inflammation. 1
Corticosteroids:
Fast-acting anti-inflammatory drugs that are used to relieve inflammation and reduce joint swelling. Corticosteroids are usually used as a short-term treatment for severe symptom flare-ups. 1
DMARDs:
(disease modifying antirheumatic drugs): These medications relieve pain and slow joint damage. DMARD medications include azathioprine, cyclosporine, and methotrexate. 1
Flare-up:
A time during which the disease is actively causing symptoms. Flare-ups are followed by periods of remission when few or no symptoms are present. 1
Health Assessment Questionnaire (HAQ):
A set of questions that assesses physical function by asking patients about their ability to do everyday activities.3
Inflammation:
Swelling and redness. Rheumatoid arthritis causes inflammation in the tissues that line the joints.4
Lyophilized:
Freeze dried. When CIMZIA is given by a doctor or nurse it is in the form of a lyophilized powder before it is mixed with sterile water and injected.5
Methotrexate:
May be prescribed alone or in combination with a biologic. It may stay in the body longer than other traditional DMARDs.1
NSAIDs:
A type of pain reliever that is often available without a prescription as capsules, pills, or tablets. Commonly used over-the-counter NSAIDs include aspirin, ibuprofen, and naproxen sodium. Other NSAIDs require a prescription from a doctor. 1
PEGylation:
A process of attaching a compound called polyethylene glycol (PEG) to the molecules of a protein to extend the length of time the drug stays in the body.6
Rheumatoid arthritis (RA):
A disease that causes inflammation, swelling, and pain in the joints.1
Rheumatologist:
A doctor who specializes in treating arthritis and other diseases that affect the joints and the muscles.1
Subcutaneous injection:
An injection that is given under the skin.1
Synovium:
Tissue that lines the joints. Swelling of the synovium can cause damage to the bone, tendons, and cartilage.3
Tumor necrosis factor-alpha (TNF-alpha):
A protein called a cytokine that triggers inflammation.1
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